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Antigenic Specificity | Caspase 1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | n/a |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Caspase family of cysteine proteases has been shown to play a key role in apoptosis. Caspase 1 (ICE, interleukin 1 converting enzyme) is the mammalian caspase responsible for the proteolytic conversion of the proforms of interleukin 1 and IL 18 into active cytokines. Like other caspases, Caspase 1 itself is synthesized as a pro enzyme that is cleaved during activation into a large (20 kDa) and small (10 kDa) subunits. The cellular role of Caspase 1 appears limited to cytokine activation as they do not have obvious roles in apoptosis. |
Immunogen | Immunogen: Caspase 1 antibody was raised in Rabbit using a synthetic peptide corresponding to a sequence at the N-terminal of human Caspase 1(p20) as the immunogen |
Other Names | [Affinity Purified Rabbit Caspase 1; Caspase 1; Caspase 1; Caspase-1; Caspase -1; Caspase -1; Caspase 1; Caspase 1; Caspase 1; Cysteine-Aspartic Acid Protease] |
Gene, Accession # | [CASP-1], Gene ID: 25166 |
Catalog # | MBS5312758 |
Price | $345 |
Order / More Info | Caspase 1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |