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Antigenic Specificity | SOS1 (Center) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | unconjugated |
Size | 0.08 mL, 0.4 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This SOS1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 934-962 amino acids from the Central region of human SOS1. Son of Sevenless 1 protein is an activator of ras proteins by stimulating the exchange of GDP for GTP on ras. Murine Son of Sevenless proteins have been shown to form a complex with activated EGF receptor, coupling tyrosine kinases to ras proteins. The SOS gene was originally isolated in Drosophila. Two mammalian homologues (mSOS1 and mSOS2) have been isolated from a mouse cDNA library and are expressed in a variety of mouse embryo and adult tissues. Human SOS1 and SOS2 homologs have also been isolated. The two mouse homologs are approximately 70% identical in composition. The mamm |
Immunogen | n/a |
Other Names | [Peptide Affinity Purified Rabbit (Pab); Son of sevenless homolog 1; SOS-1; SOS1] |
Gene, Accession # | [SOS1], Gene ID: 6654, NCBI: NP_005624.2, UniProt: Q07889 |
Catalog # | MBS9215834 |
Price | $165, $370 |
Order / More Info | SOS1 (Center) Antibody from MYBIOSOURCE INC. |
Product Specific References | Roberts A.E., et.al., Nat. Genet. 39:70-74(2007). |