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Antigenic Specificity | CD80 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: CD80 antibody detects endogenous levels of total CD80. Function: Involved in the costimulatory signal essential for T-lymphocyte activation. T-cell proliferation and cytokine production is induced by the binding of CD28, binding to CTLA-4 has opposite effects and inhibits T-cell activation.Subunit Structure: Homodimer; CD80 dimers on the antigen presenting cells (APCs) bridge CTLA4/CD152 dimers on T-cells in a periodic zipper-like arrangement. |
Immunogen | Immunogen: A synthesized peptide derived from human CD80 Subcellular Location: Membrane. Tissue Specificity: Expressed on activated B-cells, macrophages and dendritic cells. |
Other Names | [Activation B7-1 antigen; B lymphocyte activation antigen B7; B7; B7-1; B7-1 antigen; B7.1; BB1; CD28 antigen ligand 1; CD28LG; CD28LG1; CD80; CD80 antigen (CD28 antigen ligand 1, B7-1 antigen); CD80 antigen; CD80 molecule; CD80_HUMAN; Costimulatory factor CD80; costimulatory molecule variant IgV-CD80; CTLA-4 counter-receptor B7.1; LAB7; T-lymphocyte activation antigen CD80] |
Gene, Accession # | [CD80], Gene ID: 941, NCBI: NP_005182.1, UniProt: P33681 |
Catalog # | MBS9608264 |
Price | $240, $280 |
Order / More Info | CD80 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |