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Antigenic Specificity | MARK3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total MARK3 protein. Involved in the specific phosphorylation of microtubule-associated proteins for tau, MAP2 and MAP4. Phosphorylates CDC25C on 'Ser-216'. Regulates localization and activity of some histone deacetylases by mediating phosphorylation of HDAC7, promoting subsequent interaction between HDAC7 and 14-3-3 and export from the nucleus.Peng C.Y., Cell Growth Differ. 9:197-208(1998).Sun T.-Q., Nat. Cell Biol. 3:628-636(2001).Wissing J., Mol. Cell. Proteomics 6:537-547(2007) |
Immunogen | Immunogen Type: Peptide Immunogen Description: Synthesized peptide derived from N-terminal of human MARK3. |
Other Names | [C-TAK1; Cdc25C-associated protein kinase 1; EC 2.7.11.1; MAP/microtubule affinity-regulating kinase 3; Protein kinase STK10] |
Gene, Accession # | [MARK3], Gene ID: 4140, NCBI: NP_001122390.2, UniProt: P27448 |
Catalog # | MBS9401187 |
Price | $200, $255 |
Order / More Info | MARK3 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |