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Antigenic Specificity | Fas Ligand |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Description: Rabbit IgG polyclonal antibody for Tumor necrosis factor ligand superfamily member 6(FASLG) detection. Tested with WB, IHC-P in Human. Background: Fas ligand(FasL or CD95L) is a type-II transmembrane protein that belongs to the tumor necrosis factor(TNF) family. Its binding with its receptor induces apoptosis. The human FASL gene consists of approximately 8 kb and is split into 4 exons. Fas ligand/receptor interactions play an important role in the regulation of the immune system and the progression of cancer. Fas ligand or FasL is a homotrimeric type II transmembrane protein. It signals through trimerization of FasR, which spans the membrane of the target cell. This trimerization usually leads to apoptosis, or cell death. So |
Immunogen | Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human Fas Ligand (263-281aa ELSLVNFEESQTFFGLYKL). |
Other Names | [Tumor necrosis factor ligand superfamily member 6; Fas ligand(TNF superfamily, member 6); ALPS1B; APO1L; Apoptosis(APO 1) antigen ligand 1; Apoptosis antigen ligand 1; Apoptosis antigen ligand; APT1LG1; APTL; CD178; CD178 antigen; CD95 ligand; CD95-L; CD95L; CD95L protein; FAS antigen ligand; Fas L; Fas ligand(TNF superfamily member 6); Fas ligand; FASL; Fasl Fas ligand(TNF superfamily member 6); FASLG; Generalized lymphoproliferative disease; Gld; soluble form; TNF superfamily member 6; TNFL6_HUMAN; TNFSF6; Tumor necrosis factor(ligand) superfamily member 6; Tumor necrosis factor ligand superfamily member 6], [FASLG; FASLG; APTL; FASL; CD178; CD95L; ALPS1B; CD95-L; TNFSF6; APT1LG1; APT1LG1; CD95L; FASL; TNFSF6; APTL; CD95-L; Fas ligand; FasL; sFasL; APL; FasL ICD; SPA] |
Gene, Accession # | [FASLG], Gene ID: 356, NCBI: P48023.1, UniProt: P48023 |
Catalog # | MBS175611 |
Price | $315 |
Order / More Info | Fas Ligand Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |