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Antigenic Specificity | SAP97 |
Clone | polyclonal |
Host Species | n/a |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: No cross reactivity with other proteins. Description: Rabbit IgG polyclonal antibody for Disks large homolog 1(DLG1) detection. Tested with WB, IHC-P in Human;Mouse;Rat. Background: Disks large homolog 1 (DLG1), also known as synapse-associated protein 97 or SAP97, is a protein that in humans is encoded by the SAP97 gene. SAP97 is expressed throughout the body in epithelial cells, including the kidney and brain. There is some evidence that SAP97 regulates cell-to-cell adhesion during cell death, and may interact with HPV. In the brain, SAP97's function is involved in the trafficking of transmembrane receptors from the ER to the plasma membrane. SAP97's function has been investigated by reducing its expression by knockout or inc |
Immunogen | Immunogen: E Coli-derived human SAP97 recombinant protein (Position: M1-A165). Human SAP97 shares 89.7% and 84.2% amino acid (aa) sequence identity with mouse and rat SAP97, respectively. Ig Type: Rabbit IgG |
Other Names | [Disks large homolog 1; Discs large homolog 1; discs large, Drosophila, homolog of, 1; discs, large homolog 1 (Drosophila); Disks large homolog 1; dJ1061C18.1.1; DKFZp761P0818; DKFZp781B0426; DLG 1; DLG1; DLG1_HUMAN; DLGH 1; DLGH1; HDLG; Presynaptic protein SAP97; SAP 97; SAP-97; SAP97; Synapse associated protein 97; Synapse-associated protein 97; discs, large homolog 1 (Drosophila)], [DLG1; DLG1; hdlg; DLGH1; SAP97; SAP-97; dJ1061C18.1.1; SAP-97; SAP97] |
Gene, Accession # | [SAP97], Gene ID: 1739, NCBI: NP_001091894.1, UniProt: Q12959 |
Catalog # | MBS178053 |
Price | $315 |
Order / More Info | SAP97 Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Muller BM; Kistner U; Veh RW et al. (March 1995). Molecular characterization and spatial distribution of SAP97, a novel presynaptic protein homologous to SAP90 and the Drosophila discs-large tumor suppressor protein. J. Neurosci. 15 (3 Pt 2): 2354-66. 2. umbaugh G, Sia GM, Garner CC, Huganir RL (June 2003). Synapse-associated protein-97 isoform-specific regulation of surface AMPA receptors and synaptic function in cultured neurons. J. Neurosci. 23 (11): 4567-76. 3. Sans N, Racca C, Petralia RS, Wang YX, McCallum J, Wenthold RJ (October 2001). Synapse-associated protein 97 selectively associates with a subset of AMPA receptors early in their biosynthetic pathway. J. Neurosci. 21 (19): 7506-16. |