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Antigenic Specificity | BAP31 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mg |
Concentration | 1 mg/mL |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | BAP31 Antibody: Bap31 and the related protein Bap29 are endoplasmic reticulum (ER) and ER-vesicle membrane proteins and members of the B-cell receptor-associated protein family. These two proteins are highly homologous and can form homo- and heterodimers. Bap31 is thought to be involved in the intracellular trafficking of several molecules such as MHC Class I molecules and CD11b/CD18. It may also play a role in the initiation of ER stress-induced apoptosis through its association with caspase-8 via a death effector domain in its cytoplasmic tail, possibly through the promotion of membrane fragmentation and the release of cytochrome c from mitochondria. Bap31 itself contains two caspase cleavage sites and is cleaved during apoptosis. The p20 |
Immunogen | Immunogen: BAP31 antibody was raised against a 17 amino acid synthetic peptide from near the carboxy terminus of human BAP31. Buffer: BAP31 Antibody is supplied in PBS containing 0.02% sodium azide. |
Other Names | [BAP31; CDM; DDCH; BAP31; 6C6-AG; DXS1357E; B-cell receptor-associated protein 31; 6C6-AG tumor-associated antigen; BCR-associated protein 31; B-cell receptor-associated protein 31], [BCAP31; BCAP31; CDM; DDCH; BAP31; 6C6-AG; DXS1357E; BAP31; DXS1357E; BCR-associated protein 31; Bap31] |
Gene, Accession # | [BCAP31], Gene ID: 10134, NCBI: NP_005736, UniProt: P51572 |
Catalog # | MBS150797 |
Price | $375 |
Order / More Info | BAP31 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |