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Antigenic Specificity | CDH1 |
Clone | [813CT11.1.3] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | ascites |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Purified His-tagged CDH1 protein was used to produced this monoclonal antibody. Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH1 is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells. Has a potent invasive suppressor role. It is a ligand for integrin alpha-E/beta-7.E-Cad/CTF2 promotes non-amyloidogenic degradation of Abeta precursors. Has a strong inhibitory effect on APP C99 and C83 production. |
Immunogen | n/a |
Other Names | [Cadherin-1; CAM 120/80; Epithelial cadherin; E-cadherin; Uvomorulin; CD324; E-Cad/CTF1; E-Cad/CTF2; E-Cad/CTF3; CDH1; CDHE; UVO] |
Gene, Accession # | [CDH1], Gene ID: 999, NCBI: NP_004351.1, UniProt: P12830 |
Catalog # | MBS9200158 |
Price | $370 |
Order / More Info | CDH1 Antibody from MYBIOSOURCE INC. |
Product Specific References | Bussemakers M.J.G., et al. Mol. Biol. Rep. 17:123-128(1993). Oda T., et al. Proc. Natl. Acad. Sci. U.S.A. 91:1858-1862(1994). Rimm D.L., et al. Biochem. Biophys. Res. Commun. 200:1754-1761(1994). Ito K., et al. Oncogene 18:7080-7090(1999). Bussemakers M.J.G., et al. Biochem. Biophys. Res. Commun. 203:1284-1290(1994). |