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Antigenic Specificity | HP-1gamma |
Clone | 2F5 |
Host Species | Mouse |
Reactive Species | human, mouse, rat |
Isotype | IgG1 |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), Immunofluorescence (IF), Immunohistochemistry (IHC) Paraffin |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous HP-1gamma protein. At the nuclear envelope, the nuclear lamina and heterochromatin are adjacent to the inner nuclear membrane. The protein encoded by CBX3 (chromobox 3) binds DNA and is a component of heterochromatin. This protein also can bind lamin B receptor, an integral membrane protein found in the inner nuclear membrane. The dual binding functions of the encoded protein may explain the association of heterochromatin with the inner nuclear membrane. This protein binds histone H3 tails methylated at Lys-9 sites. This protein is also recruited to sites of ultraviolet-induced DNA damage and double-strand breaks. Two transcript variants encoding the same protein but differing in the 5' UTR, have been found f |
Immunogen | Immunogen: Recombinant Protein of HP-1gamma |
Other Names | [Mouse HP-1gamma Mouse (2F5); Chromobox protein homolog 3; HECH; Heterochromatin protein 1 homolog gamma; HP1 gamma; Modifier 2 protein] |
Gene, Accession # | [HP-1gamma], Gene ID: 11335, NCBI: NP_009207.2, UniProt: Q13185 |
Catalog # | MBS9700578 |
Price | $130, $220, $325 |
Order / More Info | HP-1gamma Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |