HP-1gamma Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHP-1gamma
Clone2F5
Host SpeciesMouse
Reactive Specieshuman, mouse, rat
IsotypeIgG1
Formatimmunogen affinity purified
Size0.03 mL, 0.1 mL, 0.2 mL
Concentration1 mg/ml
ApplicationsWestern Blot (WB), Immunofluorescence (IF), Immunohistochemistry (IHC) Paraffin
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DescriptionThe antibody detects endogenous HP-1gamma protein. At the nuclear envelope, the nuclear lamina and heterochromatin are adjacent to the inner nuclear membrane. The protein encoded by CBX3 (chromobox 3) binds DNA and is a component of heterochromatin. This protein also can bind lamin B receptor, an integral membrane protein found in the inner nuclear membrane. The dual binding functions of the encoded protein may explain the association of heterochromatin with the inner nuclear membrane. This protein binds histone H3 tails methylated at Lys-9 sites. This protein is also recruited to sites of ultraviolet-induced DNA damage and double-strand breaks. Two transcript variants encoding the same protein but differing in the 5' UTR, have been found f
ImmunogenImmunogen: Recombinant Protein of HP-1gamma
Other Names[Mouse HP-1gamma Mouse (2F5); Chromobox protein homolog 3; HECH; Heterochromatin protein 1 homolog gamma; HP1 gamma; Modifier 2 protein]
Gene, Accession #[HP-1gamma], Gene ID: 11335, NCBI: NP_009207.2, UniProt: Q13185
Catalog #MBS9700578
Price$130, $220, $325
Order / More InfoHP-1gamma Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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