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Antigenic Specificity | Akt2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | 100ug/100ul |
Applications | Peptide ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Akt2 antibody detects endogenous levels of Akt2 protein. Not tested with other proteins. This gene is a putative oncogene encoding a protein belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains. The gene was shown to be amplified and overexpressed in 2 of 8 ovarian carcinoma cell lines and 2 of 15 primary ovarian tumors. Overexpression contributes to the malignant phenotype of a subset of human ductal pancreatic cancers. The encoded protein is a general protein kinase capable of phophorylating several known proteins. [provided by RefSeq, Jul 2008] |
Immunogen | Immunogen: Synthetic peptide conjugated to KLH |
Other Names | [Homo sapiens v-akt murine thymoma viral oncogene homolog 2 (AKT2), transcript variant 1, mRNA; RAC-beta serine/threonine-protein kinase; RAC-beta serine/threonine-protein kinase; PKB beta; RAC-PK-beta; murine thymoma viral (v-akt) homolog-2; protein kinase Akt-2; protein kinase B beta; rac protein kinase beta; v-akt murine thymoma viral oncogene homolog 2; Protein kinase Akt-2; Protein kinase B beta; PKB beta; RAC-PK-beta], [AKT2; AKT2; PKBB; PRKBB; HIHGHH; PKBBETA; RAC-BETA] |
Gene, Accession # | [Akt2], Gene ID: 208, NCBI: NP_001617.1 |
Catalog # | MBS415443 |
Price | $230 |
Order / More Info | Akt2 Antibody from MYBIOSOURCE INC. |
Product Specific References | (1) Cheng,G.Z., Chan,J., Wang,Q., et al. Twist transcriptionally up-regulates AKT2 in breast cancer cells leading to increased migration, invasion, and resistance to Paclitaxel. Cancer Res. 2007;67 (5), 1979-1987 |