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Antigenic Specificity | BRD7 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Acts both as coactivator and as corepressor. May play a role in chromatin remodeling. Activator of the Wnt signaling pathway in a DVL1-dependent manner by negatively regulating the GSK3B phosphotransferase activity. Induces dephosphorylation of GSK3B at 'Tyr-216'. Down-regulates TRIM24-mediated activation of transcriptional activation by AR. Transcriptional corepressor that down-regulates the expression of target genes. Binds to target promoters, leading to increased histone H3 acetylation at 'Lys-9' (H3K9ac). Binds to the ESR1 promoter. Recruits BRCA1 and POU2F1 to the ESR1 promoter. Coactivator for TP53-mediated activation of transcription of a set of target genes. Required for TP53-mediated cell-cycle arrest in response to oncogene activ |
Immunogen | Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-95 of human BRD7 (NP 037395.2). |
Other Names | [BP75; NAG4; CELTIX1] |
Gene, Accession # | [BRD7], Gene ID: 29117, NCBI: Q9NPI1.1, UniProt: Q9NPI1 |
Catalog # | MBS8544894 |
Price | $280 |
Order / More Info | BRD7 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |