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Antigenic Specificity | CD3 |
Clone | [145-2C11] |
Host Species | Hamster |
Reactive Species | mouse |
Isotype | IgG |
Format | affinity purified |
Size | 0.1 mg |
Concentration | 500 ug/ml |
Applications | ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The 145-2C11 monoclonal antibody reacts with mouse CD3e, a 20 kDa subunit of the TCR complex. Along with the other CD3 subunits, gamma and delta, the epsilon chain is required for proper assembly, trafficking and surface expression of the TCR complex. CD3 is expressed by thymocytes in a developmentally regulated manner and by all mature T cells. Binding of 145-2C11 to TCR initiates the intracellular biochemical pathway resulting in cellular activation, proliferation, and apoptosis depending on specific conditions utilized. 145-2C11 is commonly used as a phenotypic marker for mouse T cells. |
Immunogen | n/a |
Other Names | [Armenian Hamster CD3; CD3; CD3; CD-3; CD-3; CD 3; CD3 epsilon; CD 3; CD3] |
Gene, Accession # | [CD3], NCBI: CAA72995.1, UniProt: P79951 |
Catalog # | MBS5309210 |
Price | $180 |
Order / More Info | CD3 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |