Edit |   |
---|---|
Antigenic Specificity | eIF4G (Phospho Ser1148) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Immunohistochemistry (IHC) Paraffin, ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Phospho-eIF4G (S1148) Polyclonal Antibody detects endogenous levels of eIF4G protein only when phosphorylated at S1148. The eukaryotic translation initiation factor 4 gamma 1 encoded by EIF4G1 is a component of the multi-subunit protein complex EIF4F. This complex facilitates the recruitment of mRNA to the ribosome, which is a rate-limiting step during the initiation phase of protein synthesis. The recognition of the mRNA cap and the ATP-dependent unwinding of 5'-terminal secondary structure is catalyzed by factors in this complex. The subunit encoded by this gene is a large scaffolding protein that contains binding sites for other members of the EIF4F complex. A domain at its N-terminus can also interact with the poly(A)-bindi |
Immunogen | Immunogen: Synthesized peptide derived from human eIF4G around the phosphorylation site of S1148 |
Other Names | [Rabbit eIF4G (phospho Ser1148); EIF4G1; EIF4F; EIF4G; EIF4GI; Eukaryotic translation initiation factor 4 gamma 1; eIF-4-gamma 1; eIF-4G 1; eIF-4G1; p220] |
Gene, Accession # | [eIF4G], Gene ID: 1981, NCBI: NP_886553.3, UniProt: Q04637 |
Catalog # | MBS9704727 |
Price | $130, $220, $325 |
Order / More Info | eIF4G (Phospho Ser1148) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |