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Antigenic Specificity | Human CD11b/C3 |
Clone | [Bear-1] |
Host Species | Mouse (Balb/c) |
Reactive Species | human |
Isotype | IgG1 |
Format | unconjugated |
Size | 0.1 mg |
Concentration | n/a |
Applications | Flow Cytometry (FC), Immunoprecipitation (IP) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Bear-1 reacts with the CD11b alpha chain of the CD11b/CD18. Bear-1 precipitated a 165-95-kDa complex and is found to be similar to Mo-1 (monocyte differentiation antigen). Integrin alpha M (ITGAM) is one protein subunit that forms the heterodimeric integrin alpha-M beta-2 (alphaMbeta2) molecule, also known as macrophage-1 antigen (Mac-1) or complement receptor 3 (CR3). ITGAM is also known as CR3A, and cluster of differentiation molecule 11B (CD11B). The second chain of alphaMbeta2 is the common integrin beta2 subunit known as CD18, and integrin alphaMbeta2 thus belongs to the beta2 subfamily (or leukocyte) integrins. alphaMbeta2 is expressed on the surface of many leukocytes involved in the innate immune system, including monoc |
Immunogen | Source Note: Bear-1 is a Mouse monoclonal IgG1 antibody derived by fusion of SP2/0 Mouse myeloma cells with spleen cells from a BALB/c Mouse immunized with with purified Human monocytes. |
Other Names | n/a |
Gene, Accession # | n/a |
Catalog # | MBS570201 |
Price | $415 |
Order / More Info | Human CD11b/C3 Antibody from MYBIOSOURCE INC. |
Product Specific References | G.D. Keizer, J. Borst, C.G. Figdor, H. Spits, F. Miedema, C. Terhorst and J.E. de Vries.Biochemical and functional characteristics of the Human leukocyte membrane antigen family LFA-1, Mo-1 and p150,95. Eur. J. Immunol. 15: 1142-1147, 1985. |