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Antigenic Specificity | APP |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | n/a |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Amyloid precursor protein (APP) is an integral membrane protein expressed in many tissues and concentrated in the synapses of neurons. Its primary function is not known, though it has been implicated as a regulator of synapse formation, neural plasticity and iron export. APP is best known and most commonly studied as the precursor molecule whose proteolysis generates beta amyloid (ABeta), a 39- to 42-amino acid peptide whose amyloid fibrillar form is the primary component of amyloid plaques found in the brains of Alzheimer's disease patients. |
Immunogen | Immunogen: APP antibody was raised in Rabbit using a synthetic peptide corresponding to a sequence at the N-terminal of human APP, identical to the related Rabbit and rat sequence as the immunogen |
Other Names | [Affinity Purified Goat APP; APP; APP; Amyloid Precursor Protein; APP C-terminus] |
Gene, Accession # | [APP] |
Catalog # | MBS5312692 |
Price | $345 |
Order / More Info | APP Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |