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Antigenic Specificity | MYH11 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: MYH11 antibody detects endogenous levels of total MYH11. Function: Muscle contraction.Subunit Structure: Muscle myosin is a hexameric protein that consists of 2 heavy chain subunits (MHC), 2 alkali light chain subunits (MLC) and 2 regulatory light chain subunits (MLC-2).Similarity: The rodlike tail sequence is highly repetitive, showing cycles of a 28-residue repeat pattern composed of 4 heptapeptides, characteristic for alpha-helical coiled coils.Limited proteolysis of myosin heavy chain produces 1 light meromyosin (LMM) and 1 heavy meromyosin (HMM). HMM can be further cleaved into 2 globular subfragments (S1) and 1 rod-shaped subfragment (S2). Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin famil |
Immunogen | Immunogen: A synthesized peptide derived from human MYH11 Subcellular Location: Melanosome. Identified by mass spectrometry in melanosome fractions from stage I to stage IV. Thick filaments of the myofibrils. Tissue Specificity: Smooth muscle; expressed in the umbilical artery, bladder, esophagus and trachea. Isoform 1 is mostly found in slowly contracting tonic muscles. Predicted Cross Reactivity: Bovine, Horse, Rabbit, Dog Similarity: Bovine (92%), Horse (100%), Rabbit (92%), Dog (92%) |
Other Names | [AAT4; DKFZp686D10126; DKFZp686D19237; FAA4; FLJ35232; MGC126726; MGC32963; MYH 11; MYH11; MYH11_HUMAN; Myosin 11; Myosin heavy chain 11; Myosin heavy chain 11 smooth muscle; Myosin heavy chain; Myosin heavy chain smooth muscle isoform; Myosin heavy polypeptide 11 smooth muscle; Myosin-11; SMHC; SMMHC; smooth muscle isoform; Smooth muscle myosin heavy chain 11 isoform SM2; Smooth muscle myosin heavy chain isoform SM2] |
Gene, Accession # | [MYH11], Gene ID: 4629, NCBI: NP_001035202.1, UniProt: P35749 |
Catalog # | MBS9608723 |
Price | $240, $280 |
Order / More Info | MYH11 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |