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Antigenic Specificity | TRIP6 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mg |
Concentration | 1 mg/mL |
Applications | ELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | TRIP6 Antibody: TRIP6 (Thyroid receptor interacting protein 6) is a zyxin-related focal adhesion molecule involved in cell motility and antiapoptotic responses. TRIP6 is predominantly expressed in kidney, liver and lung. It has three LIM domains, a PDZ-binding motif, a Crk SH2-binding motif and/or other protein interacting domains. TRIP6 regulates NF-κB activation and interacts with RICK and TRAF2, proteins that are involved in TNF signaling. TRIP6 antagonizes Fas-induced apoptosis and promotes Fas-mediated cell migration in apoptosis-resistant glioma cells via Src-dependent phosphorylation of TRIP6 at Tyr-55. |
Immunogen | Immunogen: TRIP6 antibody was raised against a 15 amino acid synthetic peptide near the center of human TRIP6. Buffer: TRIP6 Antibody is supplied in PBS containing 0.02% sodium azide. |
Other Names | [TRIP6; OIP1; OIP-1; ZRP-1; TRIP-6; TRIP6i2; OIP1; Thyroid receptor-interacting protein 6; Opa-interacting protein 1; TR-interacting protein 6; thyroid hormone receptor interactor 6], [TRIP6; TRIP6; OIP1; OIP-1; ZRP-1; TRIP-6; TRIP6i2; OIP1; TR-interacting protein 6; TRIP-6; OIP-1; ZRP-1] |
Gene, Accession # | [TRIP6], Gene ID: 7205, NCBI: NP_003293, UniProt: Q15654 |
Catalog # | MBS150280 |
Price | $375 |
Order / More Info | TRIP6 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |