CD271 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityCD271
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatpeptide affinity purified
Size0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA)
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DescriptionSpecificity: CD271 antibody detects endogenous levels of total CD271. Description: NGFR Low affinity receptor which can bind to NGF, BDNF, NT-3, and NT-4. Can mediate cell survival as well as cell death of neural cells. Homodimer; disulfide-linked. Interacts with p75NTR-associated cell death executor. Interacts with TRAF2, TRAF4, TRAF6, PTPN13 and RANBP9. Interacts through TRAF6 with SQSTM1 which bridges NGFR to NTRK1. Interacts with BEX1 and NGFRAP1/BEX3. Interacts with KIDINS220 and NTRK1.Function: Plays a role in the regulation of the translocation of GLUT4 to the cell surface in adipocytes and skeletal muscle cells in response to insulin, probably by regulating RAB31 activity, and thereby contributes to the regulation of insulin-dep
ImmunogenImmunogen: A synthesized peptide derived from human CD271 Subcellular Location: Membrane. Predicted Cross Reactivity: Pig, Bovine, Horse, Sheep, Rabbit, Dog Similarity: Pig (100%), Bovine (100%), Horse (100%), Sheep (100%), Rabbit (100%), Dog (100%)
Other Names[CD271; CD271 antigen; Gp80 LNGFR; Gp80-LNGFR; Low affinity nerve growth factor receptor; Low affinity neurotrophin receptor p75NTR; Low-affinity nerve growth factor receptor; Nerve growth factor receptor; Nerve growth factor receptor TNFR superfamily member 16; NGF receptor; Ngfr; p75 ICD; p75 Neurotrophin receptor; p75 NTR; p75(NTR); p75NTR; TNFR Superfamily Member 16; TNFRSF16; TNR16_HUMAN; Tumor necrosis factor receptor superfamily member 16]
Gene, Accession #[CD271], Gene ID: 4804, NCBI: NP_002498.1, UniProt: P08138
Catalog #MBS9600294
Price$240, $280
Order / More InfoCD271 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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