Cardiac Troponin T/TNNT2 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Cardiac Troponin T/TNNT2 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | immunogen affinity purified |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | Western Blot (WB), Direct ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: No cross reactivity with other proteins. Description: Rabbit IgG polyclonal antibody for Cardiac Troponin T detection. Tested with WB, Direct ELISA in Human; Mouse; Rat.Background: Cardiac muscle troponin T (cTnT), is a protein which in humans is encoded by the TNNT2 gene. It is mapped to 1q32.1. The protein encoded by this gene is the tropomyosin-binding subunit of the troponin complex, which is located on the thin filament of striated muscles and regulates muscle contraction in response to alterations in intracellular calcium ion concentration. Mutations in this gene have been associated with familial hypertrophic cardiomyopathy as well as with dilated cardiomyopathy. Transcripts for this gene undergo alternative splicing |
| Immunogen | Immunogen: E Coli-derived human Cardiac Troponin T recombinant protein (Position: K88-K298). |
| Other Names | [Troponin T, cardiac muscle; TnTc; Cardiac muscle troponin T; cTnT; TNNT2; Troponin T2, cardiac type] |
| Gene, Accession # | [TNNT2], Gene ID: 7139, NCBI: NP_000355.2, UniProt: P45379 |
| Catalog # | MBS1751313 |
| Price | $280 |
| Order / More Info | Cardiac Troponin T/TNNT2 Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Aviles, R. J., Askari, A. T., Lindahl, B., Wallentin, L., Jia, G., Ohman, E. M., Mahaffey, K. W., Newby, L. K., Califf, R. M., Simoons, M. L., Topol, E. J., Lauer, M. S. Troponin T levels in patients with acute coronary syndromes, with or without renal dysfunction. New Eng. J. Med. 346: 2047-2052, 2002. 2. Charlet-B, N., Logan, P., Singh, G., Cooper, T. A. Dynamic antagonism between ETR-3 and PTB regulates cell type-specific alternative splicing. Molec. Cell 9: 649-658, 2002. 3. Du, C.-K., Morimoto, S., Nishii, K., Minakami, R., Ohta, M., Tadano, N., Lu, Q.-W., Wang, Y.-Y., Zhan, D.-Y., Mochizuki, M., Kita, S., Miwa, Y., Takahashi-Yanaga, F., Iwamoto, T., Ohtsuki, I., Sasaguri, T. Knock-in mouse model of dilated cardiomyopathy caused by troponin mutation.Circ. Res. 101: 185-194, 2007. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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