Phospho-Tau (tyr 18) Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | Phospho-Tau (tyr 18) |
| Clone | [9G3] |
| Host Species | Mouse |
| Reactive Species | human, mouse, rat |
| Isotype | IgG2a |
| Format | unconjugated |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | The antibody recognizes the human Phospho-Tau protein at the tyrosine 18 phosphorylation site with no detectable cross-reactivity. Tauopathies are a group of diverse dementias and movement disorders which have a common pathological feature in that they all display the presence of intracellular accumulation of abnormal filaments of Tau protein. While the abnormal phosphorylation of Tau on serine and threonine has been well established in the disease process, its phosphorylation on tyrosine 18 has only recently been described as present in Alzheimer's disease (AD) brain. |
| Immunogen | Immunogen: Peptide |
| Other Names | n/a |
| Gene, Accession # | [Tau] |
| Catalog # | MBS588135 |
| Price | $530 |
| Order / More Info | Phospho-Tau (tyr 18) Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Schweig JE-Alzheimer's disease pathological lesions activate the spleen tyrosine kinase. 2. Liu W-miR-106b inhibits tau phosphorylation at Tyr18 by targeting Fyn in a model of Alzheimer's disease. 3. Dourlen P-Functional screening of Alzheimer risk loci identifies PTK2B as an in vivo modulator and early marker of Tau pathology. 4. Bhaskar K-Tyrosine phosphorylation of tau accompanies disease progression in transgenic mouse models of tauopathy. 5. Lee G-Phosphorylation of tau by fyn: implications for Alzheimer's disease. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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http://www.MyBioSource.com
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