SOD (EC) Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | SOD (EC) |
| Clone | [4GG11G6] |
| Host Species | Mouse |
| Reactive Species | human, rat, mouse |
| Isotype | IgG1 kappa |
| Format | streptavidin conjugate |
| Size | 0.1 mg |
| Concentration | 1mg/mL |
| Applications | Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC), Immunocytochemistry (ICC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Background Info: Detects EC SOD at ~35kDa. Does not cross react with other SODs. Scientific Background: Superoxide dismutase (SOD) is an endogenously produced intracellular enzyme present in almost every cell in the body (3). It works by catalyzing the dismutation of the superoxide radical O2 to O2 and H2O2, which are then metabolized to H2O and O2 by catalase and glutathione peroxidase (2, 5). In general, SODs play a major role in antioxidant defense mechanisms (4). There are three types of SOD in mammalian cells. One form (SOD1) contains Cu and Zn ions as a homodimer and exists in the cytoplasm. The two subunits of 16 kDa each are linked by two cysteines forming an intra-subunit disulphide bridge (3). The second form (SOD2) is a manganes |
| Immunogen | n/a |
| Other Names | [EC-SOD; MGC20077; EC 1.15.1.1; SOD3; EC SOD], [SOD3; SOD3; EC-SOD; EC-SOD] |
| Gene, Accession # | Gene ID: 6649, NCBI: NP_003093.2, UniProt: P08294 |
| Catalog # | MBS800091 |
| Price | $430 |
| Order / More Info | SOD (EC) Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Adachi T., et al. (1992) Clin Chim Acta. 212: 89-102. 2. Barrister J.V., et al. (1987). Crit. Rev. Biochem. 22:111-180. 3. FurukawaY., and O'Halloran T. (2006) Antioxidants & Redo Signaling. 8(5): 6. 4. Gao B., et al. (2003) Am J Physiol Lung Cell Mol Physiol 284: L917-L925. 5. Hassan H.M. (1988) Free Radical Biol. Med. 5: 377-385. 6. Wispe J.R., et al. (1989) BBA. 994: 30-36. 7. Regan, E. et al. (2005) Arthritis & Rheumatism 52(11): 3479-3491 1. Tollefson, A.K. et al. (2010). Endogenous enzymes (NOX and ECSOD) regulate smoke-induced oxidative stress. Free Radical Biol and Med. 49 (12), 1937-1946. doi.org/10.1016/j.freeradbiomed.2010.09.022 2. Konior, A. et al. (2011). Seasonal superoxide overproduction and endothelial activation in guinea-pig heart; seasonal oxidative stress in rats and humans. J Mol Cel Cardiology. 50 (4), 686-694. doi:10.1016/j.yjmcc.2010.11.010 |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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