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Antigenic Specificity | BTLA |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mg |
Concentration | 1 mg/mL |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: BTLA antibody is human specific. At least two isoforms of BTLA are known to exist. The B- and T-lymphocyte attenuator (BTLA) protein is a member of the immunoglobulin superfamily containing a single immunoglobulin (Ig) domain (1). Like other coihibitory receptors such as CTLA-4 and PD-1, BTLA functions as a receptor that relays inhibitory signals to suppress the immune response, and can inhibit LPS-induced endotoxic shock by suppressing TLR4 signaling in innate immune cells (1,2). Polymorphisms in this gene have also been associated with an increased risk of rheumatoid arthritis (3). |
Immunogen | Immunogen: BTLA antibody was raised against a 17 amino acid peptide near the center of human BTLA. Buffer: BTLA Antibody is supplied in PBS containing 0.02% sodium azide. |
Other Names | [BTLA : BTLA1; CD272; B- and T-lymphocyte attenuator; B- and T-lymphocyte-associated protein; B and T lymphocyte associated], [BTLA; BTLA; BTLA1; CD272] |
Gene, Accession # | [BTLA], Gene ID: 151888, NCBI: NP_861445, UniProt: Q7Z6A9 |
Catalog # | MBS153484 |
Price | $375 |
Order / More Info | BTLA Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |