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Antigenic Specificity | TAK1 |
Clone | [3G1-C4-E10] |
Host Species | Mouse |
Reactive Species | human, mouse, rat, monkey |
Isotype | IgG2b |
Format | affinity purified |
Size | 0.1 mL |
Concentration | 1.8mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Entrez Summary: The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase mediates the signaling transduction induced by TGF beta and morphogenetic protein (BMP), and controls a variety of cell functions including transcription regulation and apoptosis. In response to IL-1, this protein forms a kinase complex including TRAF6, MAP3K7P1/TAB1 and MAP3K7P2/TAB2; this complex is required for the activation of nuclear factor kappa B. This kinase can also activate MAPK8/JNK, MAP2K4/MKK4, and thus plays a role in the cell response to environmental stresses. Four alternatively spliced transcript variants encoding distinct isoforms have been reported. UniPort Summary Function: Serine/threonine kinase whic |
Immunogen | Immunogen: Purified recombinant human TAK1 protein fragments expressed in E Coli. Sensitivity: This antibody detects endogenous levels of TAK1 and does not cross-react with related proteins. Sequence Similarities: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. |
Other Names | [M3K7_HUMAN; MAP3K 7; Map3k7; MEKK7; Mitogen activated protein kinase kinase kinase 7; Mitogen-activated protein kinase kinase kinase 7; TAK1; TGF beta activated kinase 1; TGF-beta-activated kinase 1; TGF1a; Transforming growth factor beta activated kinase 1; Transforming growth factor-beta-activated kinase 1], [MAP3K7; CSCF; FMD2; TAK1; MEKK7; TGF1a] |
Gene, Accession # | [TAK1], Gene ID: 6885, NCBI: NP_003179.1, UniProt: O43318 |
Catalog # | MBS475577 |
Price | $335 |
Order / More Info | TAK1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |