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Antigenic Specificity | Progesterone Receptor (Phospho-Ser294) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | epitope affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous level of Progesterone Receptor only when phosphorylated at serine 294. Progesterone receptors (PRs) are nuclear hormone receptors of the NR3C class, which also includes mineralocorticoid,glucocorticoid and androgen receptors. They exist as homodimers coupled to Hsp90 or HMGB proteins, which are shed upon activation. The major signaling pathway used by progesterone receptors is via direct DNA binding and transcriptional regulation of target genes. They can also signal by binding to other proteins, mainly with transcription factors such as NF-kappaB, AP-1 or STAT. Progesterone receptors are found in the female reproductive tract, mammary glands, brain and pituitary gland and receptor expression is induced by es |
Immunogen | Immunogen Type: Peptide-KLH Immunogen Description: Peptide sequence around phosphorylation site of serine 294 (G-R-S(p)-P-L) derived from Human Progesterone Receptor. |
Other Names | [NR3C3; PGR; PRGR; Progesterone receptor] |
Gene, Accession # | Gene ID: 5241, NCBI: NP_000917.3, UniProt: P06401 |
Catalog # | MBS9405018 |
Price | $200, $255 |
Order / More Info | Progesterone Receptor (Phospho-Ser294) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |