Progesterone Receptor (Phospho-Ser294) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityProgesterone Receptor (Phospho-Ser294)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatepitope affinity purified
Size0.05 mL, 0.1 mL
Concentration1.0 mg/ml
ApplicationsWestern Blot (WB)
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DescriptionThe antibody detects endogenous level of Progesterone Receptor only when phosphorylated at serine 294. Progesterone receptors (PRs) are nuclear hormone receptors of the NR3C class, which also includes mineralocorticoid,glucocorticoid and androgen receptors. They exist as homodimers coupled to Hsp90 or HMGB proteins, which are shed upon activation. The major signaling pathway used by progesterone receptors is via direct DNA binding and transcriptional regulation of target genes. They can also signal by binding to other proteins, mainly with transcription factors such as NF-kappaB, AP-1 or STAT. Progesterone receptors are found in the female reproductive tract, mammary glands, brain and pituitary gland and receptor expression is induced by es
ImmunogenImmunogen Type: Peptide-KLH Immunogen Description: Peptide sequence around phosphorylation site of serine 294 (G-R-S(p)-P-L) derived from Human Progesterone Receptor.
Other Names[NR3C3; PGR; PRGR; Progesterone receptor]
Gene, Accession #Gene ID: 5241, NCBI: NP_000917.3, UniProt: P06401
Catalog #MBS9405018
Price$200, $255
Order / More InfoProgesterone Receptor (Phospho-Ser294) Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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