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Antigenic Specificity | FIR |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), Immunofluorescence (IF), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: FIR Polyclonal Antibody detects endogenous levels of FIR protein. FARP2 is a Protein Coding gene. FERM RhoGEF and pleckstrin domain-containing protein 2 functions as guanine nucleotide exchange factor that activates RAC1. May have relatively low activity. Plays a role in the response to class 3 semaphorins and remodeling of the actin cytoskeleton. Plays a role in TNFSF11-mediated osteoclast differentiation, especially in podosome rearrangement and reorganization of the actin cytoskeleton. Regulates the activation of ITGB3, integrin signaling and cell adhesion. Diseases associated with FARP2 include verheij syndrome and aarskog-scott syndrome. Among its related pathways are Developmental Biology and Adherens junction. GO annotat |
Immunogen | Immunogen: Synthesized peptide derived from the internal region of human FIR at AA range: 300-380 |
Other Names | [Rabbit FIR; FARP2; KIAA0793; PLEKHC3; FERM; RhoGEF and pleckstrin domain-containing protein 2; FERM domain including RhoGEF; FIR; Pleckstrin homology domain-containing family C member 3; PH domain-containing family C member 3] |
Gene, Accession # | [FIR], Gene ID: 9855, NCBI: NP_055623.1, UniProt: O94887 |
Catalog # | MBS9702053 |
Price | $130, $220, $325 |
Order / More Info | FIR Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |