Edit |   |
Antigenic Specificity | GFAP |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Keratins (cytokeratins) are intermediate filament proteins that are mainly expressed in epithelial cells. Keratin heterodimers composed of an acidic keratin (or type I keratin, keratins 9 to 23) and a basic keratin (or type II keratin, keratins 1 to 8) assemble to form filaments (1, 2). Keratin isoforms demonstrate tissue-and differentiation-specific profiles that make them useful as biomarkers (1). Mutations in keratin genes are associated with skin disorders, liver and pancreatic diseases, and inflammatory intestinal diseases (3-6). Keratin 7 and Keratin 19 are present in hepatic and pancreatic progenitor/stem cells (7, 8). |
Immunogen | Immunogen: Fusion protein of human KRT7. Storage Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Other Names | [KRT7; CK7; K2C7; K7; MGC129731; MGC3625; SCL; Cytokeratin 7], [KRT7; KRT7; K7; CK7; SCL; K2C7; SCL; CK-7; K7] |
Gene, Accession # | [GFAP], Gene ID: 3855, NCBI: NP_005547.3, UniProt: P08729 |
Catalog # | MBS858584 |
Price | $290 |
Order / More Info | GFAP Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Moll, R. et al. (1982) Cell 31, 11-24. 2. Chang, L. and Goldman, R.D. (2004) Nat Rev Mol Cell Biol 5, 601-13. 3. Ramaekers, F.C. and Bosman, F.T. (2004) J Pathol 204, 351-4. 4. Lane, E.B. and McLean, W.H. (2004) J Pathol 204, 355-66. 5. Zatloukal, K. et al. (2004) J Pathol 204, 367-76. 6. Owens, D.W. and Lane, E.B. (2004) J Pathol 204, 377-85. 7. Iyer, A. et al. (2008) Hum. Pathol. 39, 1370-1377. 8. Meier, K. et al. (2009) Ann Anat 191, 70-82. |