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Antigenic Specificity | GAD1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous level of total GAD1 antibody. The enzyme glutamate decarboxylase (GAD) is responsible for the synthesis of the essential neurotransmitter gamma-aminobutyric acid (GABA) from L-glutamic acid (1). GAD1 (GAD67) and GAD2 (GAD65) are expressed in nervous and endocrine systems (2) and are thought to be involved in synaptic transmission (3) and insulin secretion (4), respectively. Autoantibodies against GAD2 may serve as markers for type I diabetes (5). Many individuals suffering from an adult onset disorder known as Stiff Person Syndrome (SPS) also express autoantibodies to GAD2 (6). |
Immunogen | Immunogen Type: Peptide Immunogen Description: A synthetic peptide of human GAD1. |
Other Names | [GAD; SCP; CPSQ1] |
Gene, Accession # | [GAD1], Gene ID: 2571, NCBI: NP_000808.2, UniProt: Q99259 |
Catalog # | MBS9409900 |
Price | $255 |
Order / More Info | GAD1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |