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Antigenic Specificity | ISG15 (Center R87), 72-99 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 2 |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This ISG15 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 72-99 amino acids from the Central region of human ISG15. ISG15 is secreted from monocytes in response to type I interferons and causes natural killer (NK)-cell proliferation and an augmentation of non-MCH (major histocompatibility complex)-restricted cytotoxicity. Synthesis is stimulated by IFN-alpha or IFN-beta or IFN-omega, but not IFN-gamma. ISG15 expression is also induced by overexpression of interferon regulatory factors that participate in transcriptional regulation of IFN genes, and by influenza B virus. ISG15 is secreted also by cell lines of monocyte, T-lymphocyte, B-lymphocyte, human fibroblasts, and epithelial origins. The in |
Immunogen | n/a |
Other Names | [Ubiquitin-like protein ISG15; Interferon-induced 15 kDa protein; Interferon-induced 17 kDa protein; IP17; Ubiquitin cross-reactive protein; hUCRP; ISG15; G1P2; UCRP] |
Gene, Accession # | [ISG15], Gene ID: 9636, NCBI: NP_005092.1, UniProt: P05161 |
Catalog # | MBS9201526 |
Price | $165, $370 |
Order / More Info | ISG15 (Center R87), 72-99 Antibody from MYBIOSOURCE INC. |
Product Specific References | Padovan, E., et al., Cancer Res. 62(12):3453-3458 (2002). Meraro, D., et al., J. Immunol. 168(12):6224-6231 (2002). Reich, N., et al., Proc. Natl. Acad. Sci. U.S.A. 84(18):6394-6398 (1987). Blomstrom, D.C., et al., J. Biol. Chem. 261(19):8811-8816 (1986). Clauss, I.M., et al., Cytogenet. Cell Genet. 53 (2-3), 166-168 (1990). |