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Antigenic Specificity | APEX1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous level of total APEX1 protein. Ape1 (Apurinic/Apyrimidic eEndonuclease 1), also known as Ref1 (Redox effector factor 1), is a multifunctional protein with several biological activities. These include roles in DNA repair and in the cellular response to oxidative stress. Ape1 initiates the repair of abasic sites and is essential for the base excision repair (BER) pathway (1). Repair activities of Ape1 are stimulated by interaction with XRCC1 (2), another essential protein in BER. Ape1 functions as a redox factor that maintains transcription factors in an active, reduced state but can also function in a redox-independent manner as a transcriptional cofactor to control different cellular fates such as apoptosis, p |
Immunogen | Immunogen Type: Recombinant Protein Immunogen Description: Recombinant protein of human APEX1. |
Other Names | [APEX1; APE; APE1; APEN; APEX] |
Gene, Accession # | [APEX1], Gene ID: 328, NCBI: NP_001231178.1, UniProt: P27695 |
Catalog # | MBS9406587 |
Price | $255 |
Order / More Info | APEX1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |