Human VEGFR-2/KDR, Antagonistic Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHuman VEGFR-2/KDR, Antagonistic
Clone[6B11]
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG1
FormatProtein G purified
Size0.2 mg
Concentrationn/a
ApplicationsWestern Blot (WB), Attenuation of VEGF-induced
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DescriptionThis antibody recognizes hVEGFR-2 in western blot and it shows no cross-reactivity with hVEGFR-1. VEGF R1 (Flt-1), VEGF R2 (KDR/Flk-1), and VEGF R3 (Flt-4) belong to the class III subfamily of receptor tyrosine kinases (RTKs). All three receptors contain seven immunoglobulin-like repeats in their extracellular domain and kinase insert domains in their intracellular region. They are best known for regulating VEGF family-mediated vasculogenesis, angiogenesis, and lymphangiogenesis. They are also mediators of neurotrophic activity and regulators of hematopoietic development. Human VEGF R2 is thought to be the primary inducer of VEGF-mediated blood vessel growth, while VEGF R3 plays a significant role in VEGF-C and VEGF-D-mediated lymphangiogen
Immunogenn/a
Other Names[Antagonistic of Human VEGFR-2 (#6B11)], [KDR; KDR; FLK1; CD309; VEGFR; VEGFR2; FLK1; VEGFR2; VEGFR-2; FLK-1; KDR]
Gene, Accession #[VEGFR-2/KDR], Gene ID: 3791, NCBI: NP_002244.1, UniProt: P35968
Catalog #MBS691002
Price$895
Order / More InfoHuman VEGFR-2/KDR, Antagonistic Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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