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Antigenic Specificity | Human VEGFR-2/KDR, Antagonistic |
Clone | [6B11] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | Protein G purified |
Size | 0.2 mg |
Concentration | n/a |
Applications | Western Blot (WB), Attenuation of VEGF-induced |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This antibody recognizes hVEGFR-2 in western blot and it shows no cross-reactivity with hVEGFR-1. VEGF R1 (Flt-1), VEGF R2 (KDR/Flk-1), and VEGF R3 (Flt-4) belong to the class III subfamily of receptor tyrosine kinases (RTKs). All three receptors contain seven immunoglobulin-like repeats in their extracellular domain and kinase insert domains in their intracellular region. They are best known for regulating VEGF family-mediated vasculogenesis, angiogenesis, and lymphangiogenesis. They are also mediators of neurotrophic activity and regulators of hematopoietic development. Human VEGF R2 is thought to be the primary inducer of VEGF-mediated blood vessel growth, while VEGF R3 plays a significant role in VEGF-C and VEGF-D-mediated lymphangiogen |
Immunogen | n/a |
Other Names | [Antagonistic of Human VEGFR-2 (#6B11)], [KDR; KDR; FLK1; CD309; VEGFR; VEGFR2; FLK1; VEGFR2; VEGFR-2; FLK-1; KDR] |
Gene, Accession # | [VEGFR-2/KDR], Gene ID: 3791, NCBI: NP_002244.1, UniProt: P35968 |
Catalog # | MBS691002 |
Price | $895 |
Order / More Info | Human VEGFR-2/KDR, Antagonistic Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |