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Antigenic Specificity | SETD2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP), CHIP |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein belonging to a class of huntingtin interacting proteins characterized by WW motifs. This protein is a histone methyltransferase that is specific for lysine-36 of histone H3, and methylation of this residue is associated with active chromatin. This protein also contains a novel transcriptional activation domain and has been found associated with hyperphosphorylated RNA polymerase II. |
Immunogen | Immunogen: Recombinant Protein |
Other Names | [HYPB; SET2; HIF-1; HIP-1; KMT3A; HBP231; HSPC069; p231HBP], [SETD2; SETD2; HYPB; SET2; HIF-1; HIP-1; KMT3A; HBP231; HSPC069; p231HBP; HIF1; HYPB; KIAA1732; KMT3A; SET2; HIP-1; hSET2] |
Gene, Accession # | [SETD2], Gene ID: 29072, NCBI: Q9BYW2.3, UniProt: Q9BYW2 |
Catalog # | MBS127830 |
Price | $200, $275, $430 |
Order / More Info | SETD2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |