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Antigenic Specificity | NRG1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | Protein G purified |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Direct ligand for ERBB3 and ERBB4 tyrosine kinase receptors. Concomitantly recruits ERBB1 and ERBB2 coreceptors, resulting in ligand-stimulated tyrosine phosphorylation and activation of the ERBB receptors. The multiple isoforms perform diverse functions such as inducing growth and differentiation of epithelial, glial, neuronal, and skeletal muscle cells; inducing expression of acetylcholine receptor in synaptic vesicles during the formation of the neuromuscular junction; stimulating lobuloalveolar budding and milk production in the mammary gland and inducing differentiation of mammary tumor cells; stimulating Schwann cell proliferation; implication in the development of the myocardium such as trabeculation of the developing heart. Isoform |
Immunogen | Immunogen: Recombinant human Pro-neuregulin-1, membrane-bound isoform protein (75-176AA) |
Other Names | [Pro-neuregulin-1; membrane-bound isoformPro-NRG1; Acetylcholine receptor-inducing activity; ARIA; Breast cancer cell differentiation factor p45; Glial growth factor; Her; NRG1; GGF; HGL; HRGA; NDF; SMDF] |
Gene, Accession # | [NRG1], Gene ID: 3084, NCBI: NP_001153467.1, UniProt: Q02297 |
Catalog # | MBS7049543 |
Price | $160, $235 |
Order / More Info | NRG1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |