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Antigenic Specificity | Human CDH1 |
Clone | monoclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | IgG |
Format | unconjugated |
Size | 0.06 mL, 0.12 mL, 0.2 mL |
Concentration | n/a |
Applications | ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Cadherins are calcium-dependent cell adhesion proteins which preferentially interact with themselves in a homophilic manner in connecting cells, and thus may contribute to the sorting of heterogeneous cell type. E-cadherin (E-Cad), also known as CDH1 and CD324, is a calcium-dependent cell adhesion molecule the intact function of which is crucial for the establishment and maintenance of epithelial tissue polarity and structural integrity. Mutations in CDH1 occur in diffuse type gastric cancer, lobular breast cancer, and endometrial cancer. In human cancers, partial or complete loss of E-cadherin expression correlates with malignancy. During apoptosis or with calcium influx, E-Cad is cleaved by the metalloproteinase to produce fragments of ab |
Immunogen | Immunogen: Recombinant Human E-cadherin/CDH1/Cadherin-1/E-Cad protein Buffer: 0.2 mum filtered solution in PBS with 5% trehalose |
Other Names | [CDH1 protein; Cadherin-1; cadherin-1; cadherin 1; CAM 120/80; Epithelial cadherin; E-cadherin] |
Gene, Accession # | [CDH1 ], Gene ID: 999 |
Catalog # | MBS2543880 |
Price | $215, $330, $500 |
Order / More Info | Human CDH1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |