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Antigenic Specificity | FAIM2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: FAIM2 antibody detects endogenous levels of total FAIM2. Function: Antiapoptotic protein which protects cells uniquely from Fas-induced apoptosis. Regulates Fas-mediated apoptosis in neurons by interfering with caspase-8 activation. May play a role in cerebellar development by affecting cerebellar size, internal granular layer (IGL) thickness, and Purkinje cell (PC) development.Subunit Structure: Interacts with FAS/TNFRSF6 and BAX.Similarity: Belongs to the BI1 family. LFG subfamily. |
Immunogen | Immunogen: A synthesized peptide derived from human FAIM2 Subcellular Location: Cell Membrane. Cell Junction > Synapse > Postsynaptic Cell Membrane. Tissue Specificity: Highly expressed in breast carcinoma tissues. Enhanced expression correlates with the grade of the tumor (grade II/grade III) in primary breast tumors (at protein level). Widely expressed. Expressed at high levels in the brain especially in the hippocampus. |
Other Names | [FAIM 2; Faim2; FAIM2_HUMAN; Fas apoptotic inhibitory molecule 2; KIAA0950; LFG; Lifeguard; Neural membrane protein 35; NGP 35; NGP35; NMP 35; NMP35; Protein lifeguard; TMBIM 2; TMBIM2; Transmembrane BAX inhibitor motif containing 2; Transmembrane BAX inhibitor motif containing protein 2; Transmembrane BAX inhibitor motif-containing protein 2] |
Gene, Accession # | [FAIM2], Gene ID: 23017, NCBI: NP_036438.2, UniProt: Q9BWQ8 |
Catalog # | MBS9609832 |
Price | $240, $280 |
Order / More Info | FAIM2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |