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Antigenic Specificity | Phospho-AMPKalpha-T172 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The protein encoded by this gene belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed. |
Immunogen | Immunogen: A phospho specific peptide corresponding to residues surrounding T172 of human AMPKalpha |
Other Names | [PRKAA1 protein; 5'-AMP-activated protein kinase catalytic subunit alpha-1; 5'-AMP-activated protein kinase catalytic subunit alpha-1; protein kinase AMP-activated catalytic subunit alpha 1; Acetyl-CoA carboxylase kinase (EC:2.7.11.27); ACACA kinase; Hydroxymethylglutaryl-CoA reductase kinase (EC:2.7.11.31); HMGCR kinase; Tau-protein kinase PRKAA1 (EC:2.7.11.26)] |
Gene, Accession # | [AMPKa1], Gene ID: 5562, NCBI: AAH37303.1, UniProt: Q13131 |
Catalog # | MBS8550603 |
Price | $280 |
Order / More Info | Phospho-AMPKalpha-T172 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |