Edit |   |
---|---|
Antigenic Specificity | EndoPDI |
Clone | [2E7/7] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2a |
Format | allophycocyanin (APC) conjugate |
Size | 0.1 mg |
Concentration | 1mg/mL |
Applications | ELISA (EIA), Western Blot (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Background Info: Detects a protein with a mass of ~48kDa corresponding to EndoPDI Scientific Background: Endothelial protein disulfide isomerase (EndoPDI) is a thioredoxin member of the protein disulfide isomerase family of chaperones. This enzyme has been localized to the endoplasmic reticulum in primary endothelial cells, but colocalizes with nucleoli in the nuclei of breast, colon, and renal cancer cells. EndoPDI mRNA and protein expression is induced by hypoxia and exhibits a protective effect on endothelial cells during hypoxia (1). |
Immunogen | n/a |
Other Names | [TXNDC5; Thioredoxin domain containing 5; ERP46; UNQ364; MGC3178; FLJ21353; FLJ90810; thioredoxin related protein; endothelial protein disulphide isomeras], [TXNDC5; TXNDC5; ERP46; HCC-2; STRF8; PDIA15; UNQ364; ENDOPDI; TLP46; UNQ364/PRO700; ER protein 46; ERp46] |
Gene, Accession # | Gene ID: 81567, NCBI: NP_001139021, UniProt: Q8NBS9 |
Catalog # | MBS800296 |
Price | $435 |
Order / More Info | EndoPDI Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Sullivan D.C., et al. (2003) J Biol Chem. 278 (47) 47079-47088. |