Edit |   |
---|---|
Antigenic Specificity | ZO-3, Mid (Tight Junction-associated Polypeptide, Zonula Occludens 3) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | dog, human |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 0.1 mg |
Concentration | 0.25mg/ml |
Applications | ELISA (EL/EIA), Western Blot (WB), Immunoprecipitation (IP), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Recognizes human ZO-3 protein with a molecular weight of ~130kD. Crossreactivity with other Zonula Occluden family members has not been observed. Reactivity is con rmed with human T84, HeLa, and canine MDCK cell lysates. ZO-3, a ~130kD protein, contains three PSD-95/SAP90, discs-large, ZO-1 (PDZ) domains, a SH3 domain, and a guanylate kinase-liked domain. Like ZO-1 and ZO-2, ZO-3 contains a C-terminal acidic domain and a basic region (between the first and second PDZ domains), making it belongs to the MAGUK protein family1. By Western blot analysis, ZO-3 is identified as a ~130kDa protein that directly interacts with tight junction proteins ZO-1 and occuldin, but not with ZO-2. However, in one study, ZO-2, ZO-3 and Occludin colocalized with |
Immunogen | Immunogen: Synthetic peptide derived from the mid region of the human ZO-3 protein. |
Other Names | [-ZO-3, Mid (Tight Junction-associated Polypeptide, Zonula Occludens 3)], [TJP3; TJP3; ZO3; ZO-3; MGC119546; ZO3] |
Gene, Accession # | Gene ID: 27134, UniProt: O95049 |
Catalog # | MBS618203 |
Price | $635 |
Order / More Info | ZO-3, Mid (Tight Junction-associated Polypeptide, Zonula Occludens 3) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |