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Antigenic Specificity | PEX19 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: PEX19 antibody detects endogenous levels of total PEX19. Function: Necessary for early peroxisomal biogenesis. Acts both as a cytosolic chaperone and as an import receptor for peroxisomal membrane proteins (PMPs). Binds and stabilizes newly synthesized PMPs in the cytoplasm by interacting with their hydrophobic membrane-spanning domains, and targets them to the peroxisome membrane by binding to the integral membrane protein PEX3. Excludes CDKN2A from the nucleus and prevents its interaction with MDM2, which results in active degradation of TP53.Subunit Structure: Interacts with a broad range of peroxisomal membrane proteins, including PEX3, PEX10, PEX11A, PEX11B, PEX12, PEX13, PEX14 and PEX16, PXMP2/PMP22, PXMP4/PMP24, SLC2 |
Immunogen | Immunogen: A synthesized peptide Subcellular Location: Cytoplasm. Peroxisome Membrane. Mainly cytoplasmic. Some fraction membrane-associated to the outer surface of peroxisomes. Tissue Specificity: Ubiquitously expressed. Isoform 1 is strongly predominant in all tissues except in utero where isoform 2 is the main form. Predicted Cross Reactivity: Pig, Bovine, Horse, Dog Similarity: Pig (89%), Bovine (89%), Horse (89%), Dog (89%) |
Other Names | [33 kDa housekeeping protein; D1S2223E; HK33; Housekeeping gene 33kD; OK/SW-cl.22; PBD12A; Peroxin 19; Peroxin-19; Peroxisomal biogenesis factor 19; Peroxisomal farnesylated protein; PEX19; PEX19_HUMAN; PMP1; PMPI; PXF; PXMP1] |
Gene, Accession # | [PEX19], Gene ID: 5824, NCBI: NP_001180573.1, UniProt: P40855 |
Catalog # | MBS9605735 |
Price | $240, $280 |
Order / More Info | PEX19 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |