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Antigenic Specificity | Mcl-1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, dog, guinea pig, monkey, porcine, rabbit |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.05 mg |
Concentration | n/a |
Applications | IF, IHC (PS), WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Recognizes human, dog, guinea pig, monkey, pig and rabbit Mcl-1. Detects a band of ~42/43kDa by Western blot. Mcl-1 is a member of the Bcl-2 family that possesses anti-apoptotic activity. Mcl-1 is an immediate-early gene activated by the GMCSF as well as IL-3 signaling pathways and plays an important role in the viability response of these cytokines. Similar to all Bcl-2 family members, Mcl-1 contains BH1, BH2, and BH3 domains; however, unlike other members of this family, Mcl-1 has an extended N-terminal domain rich in PEST sequences, which probably accounts for the short half-life of this protein. |
Immunogen | Immunogen: Synthetic peptide corresponding to a portion of human Mcl-1. |
Other Names | [Mcl-1], [MCL1; MCL1; TM; EAT; MCL1L; MCL1S; Mcl-1; BCL2L3; MCL1-ES; bcl2-L-3; mcl1/EAT; BCL2L3; Bcl2-L-3] |
Gene, Accession # | [Bcl-2-like protein 3], Gene ID: 4170, NCBI: Q07820.3, UniProt: Q07820 |
Catalog # | MBS565335 |
Price | $310 |
Order / More Info | Mcl-1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |