NRG1 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | NRG1 |
| Clone | polyclonal |
| Host Species | n/a |
| Reactive Species | human |
| Isotype | n/a |
| Format | immunogen affinity purified |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Description: Rabbit IgG polyclonal antibody for Pro-neuregulin-1, membrane-bound isoform(NRG1) detection. Tested with WB in Human. Background: The protein encoded by this gene is a membrane glycoprotein that that mediates cell-cell signaling and plays a critical role in the growth and development of multiple organ systems. An extraordinary variety of different isoforms are produced from this gene through alternative promoter usage and splicing. These isoforms are expressed in a tissue-specific manner and differ significantly in their structure, and are classified as types I, II, III, IV, V and VI. Dysregulation of this gene has been linked to diseases such as cancer, schizophrenia, and bipolar disorder (BPD). |
| Immunogen | Immunogen: E Coli-derived human NRG1 recombinant protein (Position: S2-K241). Human NRG1 shares 94% amino acid (aa) sequence identity with rat NRG1. Ig Type: Rabbit IgG |
| Other Names | [Pro-neuregulin-1; Acetylcholine receptor inducing activity; Acetylcholine receptor-inducing activity; Acetylcholine receptor-inducing activity, CHICK, homolog of; ARIA; Breast cancer cell differentiation factor p45; ERBB2 p185 activator; GGF 2; GGF; GGF2; Glial growth factor; Heregulin alpha; Heregulin; heregulin, alpha (45kD, ERBB2 p185-activator); HGL; HRG 1; HRG; HRG1; HRGA; MST131; NDF; Neu differentiation factor; Neuregulin 1; neuregulin 1 type IV beta 1a; neuregulin 1 type IV beta 3; Neuregulin-1; Neuregulin1; NRG 1; nrg1; NRG1-IT2; NRG1_HUMAN; OTTHUMP00000225398; OTTHUMP00000225419; OTTHUMP00000225420; OTTHUMP00000225421; OTTHUMP00000225422; OTTHUMP00000225477; OTTHUMP00000225545; OTTHUMP00000230603; OTTHUMP00000230605; Pro neuregulin 1; Pro NRG1; pro-neuregulin-1, membrane-bound isoform; Pro-NRG1; Proneuregulin 1; ProNRG1; Sensory and motor neuron derived factor; Sensory and motor neuron-derived factor; SMDF; neuregulin 1], [NRG1; NRG1; GGF; HGL; HRG; NDF; ARIA; GGF2; HRG1; HRGA; SMDF; MST131; MSTP131; NRG1-IT2; GGF; HGL; HRGA; NDF; SMDF; Pro-NRG1; ARIA; HRG] |
| Gene, Accession # | [NRG1], Gene ID: 3084, NCBI: NP_001153467.1, UniProt: Q02297 |
| Catalog # | MBS178202 |
| Price | $280 |
| Order / More Info | NRG1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Fazzari, P., Paternain, A. V., Valiente, M., Pla, R., Lujan, R., Lloyd, K., Lerma, J., Marin, O., Rico, B.Control of cortical GABA circuitry development by Nrg1 and ErbB4 signalling. Nature 464: 1376-1380, 2010. 2. Go, R. C. P., Perry, R. T., Wiener, H., Bassett, S. S., Blacker, D., Devlin, B., Sweet, R. A. Neuregulin-1 polymorphism in late onset Alzheimer's disease families with psychoses. Am. J. Med. Genet. 139B: 28-32, 2005. |
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MYBIOSOURCE INC.
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