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Antigenic Specificity | SUZ12 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, ratpredicted: bovine, horse, sheep, rabbit, dog, chicken |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: SUZ12 Antibody detects endogenous levels of SUZ12. Description: Polycomb group (PcG) protein. Component of the PRC2/EED-EZH2 complex, which methylates 'Lys-9' (H3K9me) and 'Lys-27' (H3K27me) of histone H3, leading to transcriptional repression of the affected target gene. The PRC2/EED-EZH2 complex may also serve as a recruiting platform for DNA methyltransferases, thereby linking two epigenetic repression systems. Genes repressed by the PRC2/EED-EZH2 complex include HOXC8, HOXA9, MYT1 and CDKN2A.Post Translational Modifications: Sumoylated, probably by PIAS2.Subunit Structure: Component of the PRC2/EED-EZH2 complex, which includes EED, EZH2, SUZ12, RBBP4 and RBBP7 and possibly AEBP2. The minimum components requi |
Immunogen | Immunogen: A synthesized peptide derived from human SUZ12. Tissue Specificity: Overexpressed in breast and colon cancer. |
Other Names | [ChET 9 protein; CHET9; Chromatin precipitated E2F target 9 protein; JJAZ1; Joined to JAZF1 protein; KIAA0160; Polycomb protein SUZ12; Suppressor of zeste 12 homolog; Suppressor of zeste 12 protein homolog; SUZ12; SUZ12 polycomb repressive complex 2 subunit; SUZ12_HUMAN] |
Gene, Accession # | [SUZ12], Gene ID: 23512, NCBI: EAW80258.1, UniProt: Q15022 |
Catalog # | MBS9611510 |
Price | $240, $280 |
Order / More Info | SUZ12 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |