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Antigenic Specificity | Nr1h3 - C-terminal region |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | cow, dog, goat, guinea pig, horse, human, mouse, rabbit, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This is a rabbit polyclonal antibody against Nr1h3. It was validated on Western BlotTarget Description: Nr1h3 is an orphan receptor. Interaction with RXR shifts RXR from its role as a silent DNA-binding partner to an active ligand-binding subunit in mediating retinoid responses through target genes defined by LXRES. LXRES are DR4-type response elements characterized by direct repeats of two similar hexanuclotide half-sites spaced by four nucleotides. Nr1h3 plays an important role in the regulation of cholesterol homeostasis, regulating cholesterol uptake through MYLIP-dependent ubiquitination of LDLR, VLDLR and LRP8. |
Immunogen | n/a |
Other Names | [oxysterols receptor LXR-alpha; Oxysterols receptor LXR-alpha; oxysterols receptor LXR-alpha; nuclear receptor subfamily 1, group H, member 3; Liver X receptor alpha; Nuclear receptor subfamily 1 group H member 3] |
Gene, Accession # | [NR1H3], Gene ID: 22259, NCBI: NP_038867, UniProt: Q9Z0Y9 |
Catalog # | MBS3201092 |
Price | $335 |
Order / More Info | Nr1h3 - C-terminal region Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |