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Antigenic Specificity | Myocilin |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, monkey, mouse, rat |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mg |
Concentration | 0.75 ug/ul in antibody stabilization buffer |
Applications | Confocal Microscopy (CM), ELISA (EIA), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Secreted glycoprotein regulating the activation of different signaling pathways in adjacent cells to control different processes including cell adhesion, cell-matrix adhesion, cytoskeleton organization and cell migration. Promotes substrate adhesion, spreading and formation of focal contacts. Negatively regulates cell-matrix adhesion and stress fiber assembly through Rho protein signal transduction. |
Immunogen | Immunogen: Synthetic peptide corresponding to unique amino acid sequence on Myocilin protein. Expression: Expressed in large amounts in various types of muscle, ciliary body, papillary sphincter, skeletal muscle, heart, bone marrow-derived mesenchymal stem cells and other tissues. Expressed predominantly in the retina. In normal eyes, found in the inner uveal meshwork region and the anterior portion of the meshwork. In contrast, in many glaucomatous eyes, it is found in more regions of the meshw |
Other Names | [Glaucoma 1 open angle; GLC1A; GPOA; JOAG; Mutated trabecular meshwork-induced glucocorticoid response protein; MYOC; Myocilin; TIGR], [MYOC;] |
Gene, Accession # | NCBI: BAA24532.1, UniProt: Q99972 |
Catalog # | MBS540470 |
Price | $390 |
Order / More Info | Myocilin Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |