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Antigenic Specificity | TLR11 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse |
Isotype | n/a |
Format | ion exchange purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Toll-like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. These proteins act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors. TLR11 is one of three mouse TLRs that lack a human ortholog. It is activated specifically by uropathogenic bacteria, and mice lacking TLR11 showed a much greater susceptability to uropathogenic infections, indicating a potentially important role for TLR11 in preventing infections in the urogenital system. |
Immunogen | Immunogen Type: Peptide Immunogen Description: Raised against a peptide corresponding to 15 amino acids near the carboxy terminus of mouse TLR11. |
Other Names | [toll-like receptor 11; Toll-like receptor 11; toll-like receptor 11; toll-like receptor 11] |
Gene, Accession # | [TLR11], Gene ID: 239081, NCBI: NP_991388 |
Catalog # | MBS9404001 |
Price | $320 |
Order / More Info | TLR11 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |