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Antigenic Specificity | MRP |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: MRP antibody detects endogenous levels of total MRP. Function: Controls cell movement by regulating actin cytoskeleton homeostasis and filopodium and lamellipodium formation. When unphosphorylated, induces cell migration. When phosphorylated by MAPK8, induces actin bundles formation and stabilization, thereby reducing actin plasticity, hence restricting cell movement, including neuronal migration. May also affect cancer cell migration. May be involved in coupling the protein kinase C and calmodulin signal transduction systems (By similarity).Subunit Structure: Binds to filamentous actin (F-actin), but not to monomeric G-actin, independently of its phosphorylation status.Post-translational Modifications: Phosphorylation |
Immunogen | Immunogen: A synthesized peptide derived from human MRP Subcellular Location: Plasma Membrane Predicted Cross Reactivity: Pig, Bovine, Horse, Sheep, Rabbit, Dog Similarity: Pig (100%), Bovine (100%), Horse (100%), Sheep (100%), Rabbit (100%), Dog (100%) |
Other Names | [F52; Mac MARCKS; Mac-MARCKS; MacMARCKS; Macrophage enriched Myristoylated Alanine Rich C Kinase Substrate Like Protein; Macrophage myristoylated alanine-rich C kinase substrate; MARCKS like 1; MARCKS like protein 1; MARCKS related protein; MARCKS-like protein 1; MARCKS-related protein; MARCKSL1; MLP; MLP1; MRP; MRP_HUMAN] |
Gene, Accession # | [MRP], Gene ID: 65108, NCBI: NP_075385.1, UniProt: P49006 |
Catalog # | MBS9609118 |
Price | $240, $280 |
Order / More Info | MRP Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |