NGFR Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityNGFR
Clonepolyclonal
Host SpeciesMouse
Reactive Specieshuman
Isotypen/a
Formatunconjugated
Size0.1 mg
Concentrationn/a
ApplicationsWestern Blot (WB), Immunofluorescence (IF), Flow Cytometry (FC/FACS), ELISA (EIA)
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DescriptionNerve growth factor receptor contains an extracellular domain containing four 40-amino acid repeats with 6 cysteine residues at conserved positions followed by a serine/threonine-rich region, a single transmembrane domain, and a 155-amino acid cytoplasmic domain. The cysteine-rich region contains the nerve growth factor binding domain. NGFR p75 plays a central role in the regulation of cell number by apoptosis in the developing CNS. During early development, activation of NGFR p75 by NGF induces apoptotic cell death in some neuronal cells, probably through activation of the sphingomyelinase/ceramide pathway, the ICE like proteases and the JNK pathway. In rat Schwann cells, NGF binding to NGFR p75 activates NF kappaB, possibly to modulate Sc
ImmunogenImmunogen: Purified recombinant fragment of human NGFR expressed in E. Coli.
Other Names[CD271; p75NTR; TNFRSF16; p75(NTR); Gp80-LNGFR; NGFR], [NGFR; NGFR; CD271; p75NTR; TNFRSF16; p75(NTR); Gp80-LNGFR; TNFRSF16; NGF receptor]
Gene, Accession #[NGFR], Gene ID: 4804, NCBI: NP_002498.1, UniProt: P08138
Catalog #MBS850009
Price$280
Order / More InfoNGFR Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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