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Antigenic Specificity | IL4R (C-term) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.5 |
Applications | Western Blot (WB), ELISA (EIA), Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This IL4R antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 677-691 amino acids from the C-terminal region of human IL4R. Receptor for both interleukin 4 and interleukin 13. Couples to the JAK1/2/3-STAT6 pathway. The IL4 response is involved in promoting Th2 differentiation. The IL4/IL13 responses are involved in regulating IgE production and, chemokine and mucus production at sites of allergic inflammation. In certain cell types, can signal through activation of insulin receptor substrates, IRS1/IRS2. |
Immunogen | n/a |
Other Names | [Interleukin-4 receptor subunit alpha; IL-4 receptor subunit alpha; IL-4R subunit alpha; IL-4R-alpha; IL-4RA; CD124; Soluble interleukin-4 receptor subunit alpha; Soluble IL-4 receptor subunit alpha; Soluble IL-4R-alpha; sIL4Ralpha/prot; IL-4-binding protein; IL4-BP; IL4R; IL4RA] |
Gene, Accession # | [IL4R], Gene ID: 3566, NCBI: NP_000409.1, UniProt: P24394 |
Catalog # | MBS9201684 |
Price | $165, $370 |
Order / More Info | IL4R (C-term) Antibody from MYBIOSOURCE INC. |
Product Specific References | Idzerda R.L.,et al.J. Exp. Med. 171:861-873(1990). Galizzi J.-P.,et al.Int. Immunol. 2:669-675(1990). Kruse S.,et al.Int. Immunol. 11:1965-1970(1999). Loftus B.J.,et al.Genomics 60:295-308(1999). Ota T.,et al.Nat. Genet. 36:40-45(2004). |