Edit |   |
---|---|
Antigenic Specificity | TrkB (Phospho-Tyr515) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | epitope affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous level of TrkB only when phosphorylated at tyrosine 515. Receptor for brain-derived neurotrophic factor (BDNF), neurotrophin-3 and neurotrophin-4/5 but not nerve growth factor (NGF). Involved in the development and/or maintenance of the nervous system. This is a tyrosine-protein kinase receptor. Known substrates for the TRK receptors are SHC1, PI-3 kinase, and PLC-gamma-1. |
Immunogen | Immunogen Type: Peptide-KLH Immunogen Description: Peptide sequence around phosphorylation site of tyrosine 515 (P-Q-Y(p)-F-G) derived from Human TrkB. |
Other Names | [BDNF/NT-3 growth factors receptor precursor; GP145-TrkB; GP145-TrkB/GP95-TrkB; NTRK2; Trk-B] |
Gene, Accession # | [TrkB], Gene ID: 4915, NCBI: NP_001007098.1, UniProt: Q16620 |
Catalog # | MBS9403535 |
Price | $200, $255 |
Order / More Info | TrkB (Phospho-Tyr515) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |