Phospho-MLKL (Ser358) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Phospho-MLKL (Ser358) |
| Clone | [1D4] |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG |
| Format | Protein A purified |
| Size | 0.02 mL, 0.06 mL, 0.12 mL |
| Concentration | 1mg/mL |
| Applications | Immunohistochemistry (IHC) Paraffin (IHC-p) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This gene belongs to the protein kinase superfamily. The encoded protein contains a protein kinase-like domain; however, is thought to be inactive because it lacks several residues required for activity. This protein plays a critical role in tumor necrosis factor (TNF)-induced necroptosis, a programmed cell death process, via interaction with receptor-interacting protein 3 (RIP3), which is a key signaling molecule in necroptosis pathway. Inhibitor studies and knockdown of this gene inhibited TNF-induced necrosis. High levels of this protein and RIP3 are associated with inflammatory bowel disease in children. Alternatively spliced transcript variants have been described for this gene.MLKL (Mixed Lineage Kinase Domain Like Pseudokinase) is a |
| Immunogen | Immunogen: Synthetic Peptide of Phospho-MLKL (Ser358) Buffer: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4 Conjugation: Unconjugated |
| Other Names | [MLKL] |
| Gene, Accession # | [MLKL], Gene ID: 197259, NCBI: NP_001135969.1, UniProt: Q8NB16 |
| Catalog # | MBS2548822 |
| Price | $110, $150, $225 |
| Order / More Info | Phospho-MLKL (Ser358) Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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