Edit |   |
---|---|
Antigenic Specificity | PPP2CA |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | PP2A is the major phosphatase for microtubule-associated proteins (MAPs). PP2A can modulate the activity of phosphorylase B kinase casein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase. Cooperates with SGO2 to protect centromeric cohesin from separase-mediated cleavage in oocytes specifically during meiosis I. Can dephosphorylate SV40 large T antigen and p53/TP53. Activates RAF1 by dephosphorylating it at 'Ser-259'. |
Immunogen | Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-309 of human PPP2CA (NP 002706.1). |
Other Names | [RP-C; PP2Ac; PP2CA; PP2Calpha] |
Gene, Accession # | [PPP2CA], Gene ID: 5515, NCBI: NP_002706.1, UniProt: P67775 |
Catalog # | MBS8546303 |
Price | $280 |
Order / More Info | PPP2CA Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |